反应详情

In a similar manner as described in step 2 of Example 3, the title compound was prepared from {[6-(1,5-diphenyl-1H-pyrrol-2-yl)-2-naphthyl]oxy}acetonitrile (0.180 g, 0.373 mmol), prepared in the previous step, ammonium chloride (0.060 g, 1.12 mmol) and sodium azide (0.073 g, 1.12 mmol) in DMF (10 mL). The precipitated solids were isolated by vacuum filtration to give 5-({[6-(1,5-diphenyl-1H-pyrrol-2-yl)-2-naphthyl]oxy}methyl)-1H-tetraazole as an off-white solid (0.130 g, 98%), mp 269–270° C. (dec). Elemental Analysis for C28H21N5O Calc'd: C, 75.83; H, 4.77; N, 15.79. Found: C, 75.83; H, 4.69; N, 15.50.

1. customThe precipitated solids were isolated by vacuum filtration