HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenemethanamine, 2,4-dichloro-N-methyl- → 3-(6,8-Dichloro-2-ethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenemethanamine, 2,4-dichloro-N-methyl- | HCID 485424 | — |
| Reactant | 3-(6,8-Dichloro-2-methyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride | HCID 86672330 | — |
| Product | 3-(6,8-Dichloro-2-ethyl-1,2,3,4-tetrahydroisoquinolin-4-yl)benzene-1-sulfonyl chloride | HCID 86672345 | — |
Reaction Steps
Using procedures outlined in Example 1 to prepare intermediate 1.6, substituting N-(2,4-dichlorobenzyl)ethanamine for 1-(2,4-dichlorophenyl)-N-methylmethanamine, the title compound was prepared as a hydrochloride salt.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08541448B2 |
| Source dataset | uspto-grants-2013_09 |
| ORD ID | ord-6b9ffe09322b413fa1a1fabdbc8d32ba |
| Source note | uspto-grants-2013_09 |