HCID 22566176, compound → HCID 178468843, compound

HRID 457239Notes

Reaction equation

HRID 457239 reaction equation
[OH:1][CH:2]([CH3:16])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][NH2:15])=[CH:7][CH:6]=1.Cl.C([NH:22][C:23]([NH:25][C:26]([C:28]1[C:33]([NH2:34])=[N:32][C:31]([NH2:35])=[C:30]([Cl:36])[N:29]=1)=[O:27])=N)CCC>>[ClH:36].[OH:1][CH:2]([CH3:16])[CH2:3][O:4][C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][CH2:13][CH2:14][NH:15][C:23]([NH:25][C:26]([C:28]2[C:33]([NH2:34])=[N:32][C:31]([NH2:35])=[C:30]([Cl:36])[N:29]=2)=[O:27])=[NH:22])=[CH:7][CH:6]=1

Participants

3

Reactant 2

HCID 22566176HCID 22566176, compoundHCID 178449225HCID 178449225, compound

Product 1

HCID 178468843HCID 178468843, compound

Procedure

Using general procedure Z, 4-[4-(2-hydroxypropyloxy)phenyl]butyl amine was converted into 4-[4-(2-hydroxypropyloxy)phenyl)]butylamidino-3,5-diamino-6-chloropyrazinecarboxamide hydrochloride, m.p. 212–214° C., APCI MS, M/Z=436 [C19H26ClN7O3+H]+.

Sources & evidence

ORD record
ord-b414610b0e2d46fe9a0a3b61460bad66
Source dataset
uspto-grants-2007_03
Patent number
US07186833B2

Reaction notes

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