反应详情

温度

180 °C

(a-2) was synthesized by a dehydration amidation reaction between stearic acid and N,N-dimethyl-1,3-propanediamine. Specifically, 161 g of N,N-dimethyl-1,3-propanediamine and 373.3 g of the fatty acid were placed in a four-neck flask equipped with a stirrer, a temperature gage and a dehydrating pipe and the mixture was raised to 180° C. The mixture was stirred under heating at this temperature for about 5 hours while distilling generated water. Then, the reaction mixture was cooled to 120° C. and unreacted amine was distilled under reduced pressure to obtain the target N-stearoylaminopropyl-N,N-dimethylamine (a-2).

1. customequipped with a stirrer
2. temperatureunder heating at this temperature for about 5 hours
3. distillationwhile distilling
4. temperatureThen, the reaction mixture was cooled to 120° C.
5. distillationunreacted amine was distilled under reduced pressure