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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 457598Generated: October 29, 2026

HCID 20760150, compound → HCID 67378457, compound

https://huagongshe.com/reaction/457598

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 20760150HCID 20760150—
Reactant4-{[(2R)-2,3-Dihydroxypropyloxy]phenyl}butylamineHCID 67365743—
ProductHCID 67378457HCID 6737845799%

Reaction Steps

Compound 73 was prepared in a similar fashion to the synthesis of compound 70 starting from compound 72 (1.67 g, 4.5 mmol). Amine 73 (1.06 g, 99%) was isolated as a white solid. 1H NMR (300 MHz, DMSO-d6) δ 1.32 (m, 2H), 1.54 (m, 2H) 2.55 (m, 2H), 3.45 (m, 2H), 3.75 (m, 3H), 3.94 (m, 2H), 6.83 (d, 2H), 7.08 (d, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189719B2
Source datasetuspto-grants-2007_03
ORD IDord-174884ba832d461790c76f5063f95ecc
Source noteuspto-grants-2007_03