methyl 2-{2-[4-(1H-indol-3-yl)-piperidin-1-yl]-ethoxy}-benzoate → 2-(2-{4-[1-(tetrahydro-furan-3-ylmethyl)-1H-indol-3-yl)-piperidin-1-yl}-ethoxy)-benzoic Acid

Beteiligte Stoffe

Reaktionsschritte

This compound was prepared following the procedure described in example 1 (part E) starting with 0.1 g (0.26 mmol) of 2-{2-[4-(1H-indol-3-yl)-piperidin-1-yl]-ethoxy}-benzoic acid methyl ester and 0.067 g (0.37 mmol) of freshly prepared tetrahydro-furan-3-ylmethyl methanesulfonate. After standard purification, 0.045 g (39% of yield) of the expected acid were obtained.

Herkunft & Nachweise