HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 11229939, compound → HCID 10185005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 11229939 | HCID 11229939 | — |
| Reactant | HCID 17964388 | HCID 17964388 | — |
| Product | HCID 10185005 | HCID 10185005 | 99% |
Reaction Steps
This compound was prepared following the procedure described in example 13 (part D) starting with 0.1 g (0.31 mmol) of 6-fluoro-3-piperidin-4-yl-1-(2-thiophen-3-yl-ethyl)-1H-indole (example 78, part B) and 0.09 g (0.42 mmol) of 2-(2-chloro-ethoxy)-benzoic acid ethyl ester. After purification by HPLC-MS using a C-18 column, 0.01 g (99% of purity) of 2-(2-{4-[6-fluoro-1-(2-thiophen-3-yl-ethyl)-1H-indol-3-yl]-piperidin-1-yl}-ethoxy)-benzoic acid were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189741B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-a1add0f3e56b490bb496cd4cc0d0c274 |
| Source note | uspto-grants-2007_03 |