HuagongsheHuagongshe Chemistry Print Report · For research reference only
Aspirin → Acetic acid 2-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylcarbamoyl]-phenyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Aspirin | HCID 2244 | — |
| Reactant | 4-Methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylamine | HCID 11557499 | — |
| Product | Acetic acid 2-[4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylcarbamoyl]-phenyl ester | HCID 58820306 | 25% |
Reaction Steps
Pet-159 was prepared according to the general procedure described hereinabove and the procedure described above for the preparation of Pet-154, using 2-acetoxy-benzoic acid (Aspirin) and 4-methyl-5-(2-nitrooxy-ethyl)-thiazol-2-ylamine (Pet-10) as the starting materials, in an overall yield of 25%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189750B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-c40e9dcba1354645905701eb1f321e55 |
| Source note | uspto-grants-2007_03 |