3-Chloropropanesulphonyl chloride → HCID 18440780, compound

HRID 457897Notes

Reaction equation

HRID 457897 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13]1[N:14]=[C:15]([C:24]([CH3:28])([CH3:27])[CH2:25][NH2:26])[NH:16][C:17]=1[C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1)[CH:7]=[CH:6]2.[Cl:29][CH2:30][CH2:31][CH2:32][S:33](Cl)(=[O:35])=[O:34]>>[Cl:29][CH2:30][CH2:31][CH2:32][S:33]([NH:26][CH2:25][C:24]([C:15]1[NH:16][C:17]([C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)=[C:13]([C:8]2[CH:7]=[CH:6][C:5]3[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:9]=2)[N:14]=1)([CH3:28])[CH3:27])(=[O:35])=[O:34]

Participants

3

Reactant 2

HCID 154103-Chloropropanesulphonyl chlorideHCID 18440775HCID 18440775, compound

Product 1

HCID 18440780HCID 18440780, compoundYield 40%

Procedure

The title compound (11 mg, 40%) was prepared starting from the product of Example 2 and 3-chloro-propanesulfonyl chloride using the method described in Example 4; MS(ES) m/e 514 (M+H)+.

Sources & evidence

ORD record
ord-1d61daf82857404e93cbccf5460b71d4
Source dataset
uspto-grants-2007_03
Patent number
US07189745B1

Reaction notes

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