Acetyl isocyanate → HCID 18440766, compound

HRID 457901Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[CH:9]=[C:8]([C:13]1[N:14]=[C:15]([C:24]([CH3:28])([CH3:27])[CH2:25][NH2:26])[NH:16][C:17]=1[C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1)[CH:7]=[CH:6]2.[CH3:29][C:30]([N:32]=[C:33]=[O:34])=[O:31]>>[CH3:29][C:30]([NH:32][C:33]([NH:26][CH2:25][C:24]([C:15]1[NH:16][C:17]([C:18]2[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=2)=[C:13]([C:8]2[CH:7]=[CH:6][C:5]3[C:10](=[CH:11][CH:12]=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:9]=2)[N:14]=1)([CH3:28])[CH3:27])=[O:34])=[O:31]

Participants

Reactant 2

HCID 12300404Acetyl isocyanate

HCID 18440775HCID 18440775, compound

Product 1

HCID 18440766HCID 18440766, compoundYield 51%

Procedure

The title compound (13 mg, 51%) was prepared starting from the product of Example 2 and methylformyl isocyanate using the method described in Example 4; MS(ES) m/e 474 [M+H]+.

Sources & evidence

ORD record: ord-0b83f3114e454a5eb9760a27ae50a871
Source dataset: uspto-grants-2007_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07189745B1

Reaction notes

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