HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Amino-5-chloro-2-methoxybenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | Methyl 4-acetamido-5-chloro-2-methoxybenzoate | HCID 77721 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Amino-5-chloro-2-methoxybenzoic acid | HCID 81626 | — |
Reaction Steps
Methyl 4-acetamido-5-chloro-2-methoxybenzoate is dissolved in ethanol and aqueous potassium hydroxide added. The solution is refluxed for a short time, cooled and concentrated hydrochloric acid added. The resulting precipitate is filtered off, washed with water and dried to give the title compound as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189852B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-d35dadbfa42b41ef9a8ff4f10f5347b0 |
| Source note | uspto-grants-2007_03 |