Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 458144Generated: October 29, 2026

P-Anisidine → 1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-one

https://huagongshe.com/reaction/458144

Reaction equation

Participants

RoleNameHCIDCharge
ReactantP-AnisidineHCID 7732—
Reactant1-Benzyl-4-piperidoneHCID 19220—
Reactant1-(4-Fluorophenyl)-1,3,8-triazaspiro(4.5)decan-4-oneHCID 93915—
Product1-(4-Methoxyphenyl)-1,3,8-triazaspiro[4.5]decan-4-oneHCID 13240217—

Reaction Steps

This compound was prepared from 1-benzyl-4-piperidone and 4-methoxy-phenyl amine in analogy of the procedure described for the synthesis of 1-(4-fluoro-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one. 1-(4-Methoxy-phenyl)-1,3,8-triaza-spiro[4.5]decan-4-one was obtained as colorless solid: MS (ISP): 262.1 MH+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189850B2
Source datasetuspto-grants-2007_03
ORD IDord-a104a049944947798054786fc7915b85
Source noteuspto-grants-2007_03