HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 22341899, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Amino-2-chlorophenol | HCID 77578 | — |
| Reactant | 4-(Trifluoromethyl)-2,3,5,6-tetrafluorobenzyl bromide | HCID 127137 | — |
| Product | HCID 22341899 | HCID 22341899 | 76% |
Reaction Steps
According to the similar procedure in Synthesis Example 1, by using 4-amino-2-chlorophenol (3.00 g, 19.6 mmole), DMF (80 ml), TEA (0.5 ml), and 2,3,5,6-tetrafluoro-4-trifluoromethylbenzyl bromide (1.40 g, 8.36 mmole), 2.00 g (76.0% yield) of 2-chloro-5-(2,3,5,6-tetrafluoro-4-methylbenzylamino)phenol was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189878B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-1c30e26ae2734025ac78208d010529fe |
| Source note | uspto-grants-2007_03 |