HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 10093523, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-(Trifluoromethyl)-2,3,5,6-tetrafluorobenzyl bromide | HCID 127137 | — |
| Reactant | 4-Amino-2-hydroxybenzenesulfonic acid | HCID 219595 | — |
| Product | HCID 10093523 | HCID 10093523 | 28% |
Reaction Steps
According to the similar procedure in Synthesis Example 1, by using 4-amino-2-hydroxybenzene sulfonic acid (1.00 g, 5.30 mmole), DMF (10 ml), TEA (1.0 ml), and 2,3,5,6-tetrafluoro-4-trifluoromethylbenzyl bromide (0.88 g, 5.30 mmole), 0.61 g (28.0% yield) of 2-hydroxy-5-(2,3,5,6-tetrafluoro-4-trifluoromethylbenzylamino)benzene sulfonic acid was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07189878B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-692750d24376489a938c8f4b0d1fecad |
| Source note | uspto-grants-2007_03 |