HCID 67183996, compound → HCID 178522843, compound

Participants

Reaction Steps

N-{3-[4-pyridin-4-yl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazol-3-yl]-benzyl}-4-trifluoromethyl-benzamide (0.10 g, 0.19 mmol) was stirred in HCl 4M in dioxane at room temperature for 4 h. The solvent was evaporated under vacuum and the crude product was purified by reverse phase HPLC yielding N-[3-(4-pyridin-4-yl-1H-pyrazol-3-yl)-benzyl]-4-trifluoromethyl-benzamide (0.025 g, 0.06 mmol, 31%) as a solid.

Provenance & Evidence