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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 458323Generated: October 30, 2026

2,5-Difluorobenzaldehyde → HCID 86584841, compound

https://huagongshe.com/reaction/458323

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DifluorobenzaldehydeHCID 137663—
ReactantHCID 69431427HCID 69431427—
ProductHCID 86584841HCID 86584841—

Reaction Steps

(2S,4R)-2-aminomethyl-4-tritylsulfanyl-pyrrolidine-1-carboxylic acid benzyl ester and 2,5-difluorobenzaldehyde and subsequent cleavage of the trityl protecting group analogously to reductive amination and deprotection gave (2S,4R)-2-[(2,5-difluoro-benzylamino)-methyl]-4-mercapto-pyrrolidine-1-carboxylic acid benzyl ester as colorless oil, MS: 393 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189756B2
Source datasetuspto-grants-2007_03
ORD IDord-ee036ecdb2af4db6b99728b7c577d3c5
Source noteuspto-grants-2007_03