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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 458348Generated: October 25, 2026

Benzyl Bromide → (2S,4R)-2-benzyloxymethyl-4-tritylsulfanyl-pyrrolidine

https://huagongshe.com/reaction/458348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl BromideHCID 7498—
Reactant(2S,4R)-2-hydroxymethyl-4-tritylsulfanyl-pyrrolidine-1-carboxylic acid tert-butyl esterHCID 11271474—
Product(2S,4R)-2-benzyloxymethyl-4-tritylsulfanyl-pyrrolidineHCID 69427603—

Reaction Steps

In analogy: The reaction of (2S,4R)-2-hydroxymethyl-4-tritylsulfanyl-pyrrolidine-1-carboxylic acid tert-butyl ester with benzylbromide gave (2S,4R)-2-benzyloxymethyl-4-tritylsulfanyl-pyrrolidine, MS: 466 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07189756B2
Source datasetuspto-grants-2007_03
ORD IDord-972c1392289a4c4b9d5920bea040dbe6
Source noteuspto-grants-2007_03