反应详情

Into a 2 L flask fitted with a reflux condenser and magnetic stir-bar was introduced 2,5-dibromobenzoic acid (50.0 g, 0.1786 mol) and thionyl chloride (150 mL, 2.04 mol). The mixture was refluxed for 8 hours. Most of the thionyl chloride was distilled off followed by removal of the remainder by rotary evaporation. Distillation gave 40 g of 2,5-dibromobenzoyl chloride. (pot temperature 110° C.; distillation temp 70° C./0.70 mm Hg).

1. customInto a 2 L flask fitted with a reflux condenser and magnetic stir-bar
2. temperatureThe mixture was refluxed for 8 hours
3. distillationMost of the thionyl chloride was distilled off
4. customfollowed by removal of the remainder by rotary evaporation
5. distillationDistillation