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HRID4585

反应详情

EQUATION

反应方程式

HRID 4585 的结构方程式

REACTANTS

反应物

3
结构：CCO
HCID702

Ethanol

C2H6O

结构：CCOC(=O)/C=C(/C)N
HCID643756

未命名化合物

结构：CC1CC(OC(=O)CC(=O)C=Cc2cccc([N+](=O)[O-])c2)CC(C)(C)C1
HCID70416495

未命名化合物

PRODUCTS

生成物

1
结构：CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC2CC(C)CC(C)(C)C2)C1c1cccc([N+](=O)[O-])c1
HCID20151211

未命名化合物

收率 37%

CONDITIONS

反应条件

温度
-5 °C

PROCEDURE

实验过程

21.87 g (0.06 moles) of 3,3,5-trimethylcyclohexyl 2-(3-nitrobenzylidene)acetylacetate and 7.84 g (0.06 moles) of ethyl 3-aminocrotonate are heated under reflux in 60 ml of ethanol for 8 hours. The solution is then cooled to -5° C. to obtain 3,3,5-trimethylcyclohexyl 2,6-dimethyl-5-ethoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate as yellow crystals melting--after recrystallisation in ethanol--at 125°-129° C. The yield is 37% of the theoretical yield.