HuagongsheHuagongshe Chemistry Print Report · For research reference only
Toluene → 5,7-dimethyl-2-oxo-3(2H)-Benzoxazoleacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Toluene | HCID 1140 | — |
| Reactant | tert-Butyl (5,7-dimethyl-2-oxo-1,3-benzoxazol-3(2H)-yl)acetate | HCID 57436180 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 5,7-dimethyl-2-oxo-3(2H)-Benzoxazoleacetic acid | HCID 18442655 | — |
Reaction Steps
A solution of the tert-butyl (5,7-dimethyl-2-oxo-1,3-benzoxazol-3(2H)-yl)acetate from Step B in CH2Cl2 (0.7 mL) and CF3CO2H (0.3 mL) was stood at ambient temperature for 2 h. Toluene (5 mL) was added and the mixture was conc. in vacuo to give the title compound as a dark solid. MS: m/z=222 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192954B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-2b036845640b4ecfbfba97e9f877fe11 |
| Source note | uspto-grants-2007_03 |