Methyl iodide → 1-Benzyl-1-methyl-4-oxopiperidinium iodide

Participants

Reaction Steps

To 9.79 ml of 1-benzyl-4-piperidone, 16.5 ml of methyl iodide was added and stirred for 16 hours at room temperature. To the resulting yellow suspension, approx. 10 ml of ether was added and the formed yellow solid was recovered by filtration, which solid was washed with ether and dried to provide 13.42 g of the title compound as a yellow powder.

Provenance & Evidence