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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 458854Generated: November 3, 2026

[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-phenyl-acetic acid → 2-[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-2-phenyl-N-pyrazin-2-ylmethyl-acetamide

https://huagongshe.com/reaction/458854

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-phenyl-acetic acidHCID 18442565—
ReactantPyrazin-2-ylmethanamine hydrochlorideHCID 21265794—
Product2-[1-(3,4-Dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-2-phenyl-N-pyrazin-2-ylmethyl-acetamideHCID 10303734—

Reaction Steps

prepared by reaction of [1-(3,4-dimethoxy-benzyl)-7,8-dimethoxy-1,3,4,5-tetrahydro-benzo[c]azepin-2-yl]-phenyl-acetic acid with C-pyrazin-2-yl-methylamine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192950B2
Source datasetuspto-grants-2007_03
ORD IDord-78f93714d7854aed8edd189854acea59
Source noteuspto-grants-2007_03