Benzene, (3-bromopropoxy)- → HCID 10443501, compound

HRID 458898Notes

Reaction equation

HRID 458898 reaction equation
[NH:1]1[CH2:5][CH2:4][C@@H:3]([OH:6])[CH2:2]1.Br[CH2:8][CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[O:11]([CH2:10][CH2:9][CH2:8][N:1]1[CH2:5][CH2:4][C@@H:3]([OH:6])[CH2:2]1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 68522Benzene, (3-bromopropoxy)-HCID 2759337(R)-3-Pyrrolidinol

Product 1

HCID 10443501HCID 10443501, compoundYield 71.3%

Procedure

Prepared as in Intermediate I-15 from (3R)pyrrolidin-3-ol (commercially available) and (3-bromopropoxy)benzene. The yield was 2.26 g (71.3%) of the title compound.

Sources & evidence

ORD record
ord-ef916534b7764858be311b28dfe14230
Source dataset
uspto-grants-2007_03
Patent number
US07192978B2

Reaction notes

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