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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 458899Generated: October 30, 2026

(R)-3-Pyrrolidinol → (3R)-1-(3-thien-2-ylpropyl)pyrrolidin-3-ol

https://huagongshe.com/reaction/458899

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(R)-3-PyrrolidinolHCID 2759337—
ReactantHCID 11557512HCID 11557512—
Product(3R)-1-(3-thien-2-ylpropyl)pyrrolidin-3-olHCID 1182047285%

Reaction Steps

Prepared as in Intermediate I-15 from (3R)pyrrolidin-3-ol (commercially available) and 2-(3-bromopropyl)thiophene. The yield was 1.02 g (85%) of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192978B2
Source datasetuspto-grants-2007_03
ORD IDord-437a5c409c314098b06d3a146dcb77e0
Source noteuspto-grants-2007_03