HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-prop-1-ynyl]-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Hydroxyflavone | HCID 5281894 | — |
| Reactant | (2S)-3-[4-(3-Chloro-prop-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 58822943 | — |
| Product | (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-prop-1-ynyl]-phenyl}-propionic acid | HCID 10139033 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(3-Chloro-prop-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 5, Step A and 7-hydroxyflavone in a manner analogous to that described for Example 5, Step B. MS(ES) for C28H22O6[M+H]+: 455.2.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-df4e920275ed4cb5be23efca57b0f303 |
| Source note | uspto-grants-2007_03 |