Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459095Generated: October 25, 2026

7-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[5-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-pent-1-ynyl]-phenyl}-propionic acid

https://huagongshe.com/reaction/459095

Reaction equation

Participants

RoleNameHCIDCharge
Reactant7-HydroxyflavoneHCID 5281894—
Reactant3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 69421973—
Product(2S)-2-Methoxy-3-{4-[5-(4-oxo-2-phenyl-4H-chromen-7-yloxy)-pent-1-ynyl]-phenyl}-propionic acidHCID 69424192—

Reaction Steps

The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24, Step A and 7-hydroxyflavone in a manner analogous to that described for Example 24, Step B. MS(ES) for C30H26O6[M+H]+:483.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-a475a4d160834725828f465f2d741a74
Source noteuspto-grants-2007_03