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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459096Generated: October 26, 2026

6-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[5-(4-oxo-2-phenyl-4H-chromen-6-yloxy)-pent-1-ynyl]-phenyl}-propionic acid

https://huagongshe.com/reaction/459096

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-HydroxyflavoneHCID 72279—
Reactant3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 69421973—
Product(2S)-2-Methoxy-3-{4-[5-(4-oxo-2-phenyl-4H-chromen-6-yloxy)-pent-1-ynyl]-phenyl}-propionic acidHCID 58822631—

Reaction Steps

The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24, Step A and 6-hydroxyflavone in a manner analogous to that described for Example 24, Step B. MS(ES) for C30H26O6[M+H]+:483.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-bee694d5e8d6403c9885275e490a9db3
Source noteuspto-grants-2007_03