Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459098Generated: October 26, 2026

3-Hydroxy-N-phenylaniline → (2s)-2-Methoxy-3-{4-[5-(3-phenylamino-phenoxy)-pent-1-ynyl]-phenyl}-propionic acid

https://huagongshe.com/reaction/459098

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Hydroxy-N-phenylanilineHCID 7546—
Reactant3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 69421973—
Product(2s)-2-Methoxy-3-{4-[5-(3-phenylamino-phenoxy)-pent-1-ynyl]-phenyl}-propionic acidHCID 59015146—

Reaction Steps

The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24 Step A and 3-hydroxydiphenylamine in a manner analogous to that described for Example 24, Step B. MS(ES) for C27H27NO4[M+H]+:430.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-92b2bc762cc142678fab7bee0b5c8e35
Source noteuspto-grants-2007_03