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2-Fluoro-4'-hydroxybenzophenone → (2S)-3-(4-{5-[4-(2-Fluoro-benzoyl)-phenoxy]-pent-1-ynyl}-phenyl)-2-methoxy-propionic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Fluoro-4'-hydroxybenzophenone | HCID 2783235 | — |
| 反応物 | 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 69421973 | — |
| 生成物 | (2S)-3-(4-{5-[4-(2-Fluoro-benzoyl)-phenoxy]-pent-1-ynyl}-phenyl)-2-methoxy-propionic acid | HCID 58822681 | — |
反応手順
The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24, Step A and 2-fluoro-4′-hydroxybenzophenone in a manner analogous to that described for Example 24, Step B. MS(ES) for C28H25FO5[M+H]+:461.2.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07192982B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-e5cfa7a924614a2f9ad0d39616fefe32 |
| 出典メモ | uspto-grants-2007_03 |