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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459100Generated: October 25, 2026

Benzyl-4-hydroxyphenylketone → (2S)-2-Methoxy-3-{4-[5-(4-phenylacetyl-phenoxy)-pent-1-ynyl]-phenyl}-propionic acid

https://huagongshe.com/reaction/459100

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzyl-4-hydroxyphenylketoneHCID 54326216—
Reactant3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 69421973—
Product(2S)-2-Methoxy-3-{4-[5-(4-phenylacetyl-phenoxy)-pent-1-ynyl]-phenyl}-propionic acidHCID 58822612—

Reaction Steps

The title compound was prepared from 3-[4-(5-Bromo-pent-1-ynyl)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 24, Step A and benzyl-4-hydroxyphenylketone in a manner analogous to that described for Example 24, Step B. MS(ES) for C29H25O5[M−H]−:455.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-5ebec48347574836aae59a315dc78fbd
Source noteuspto-grants-2007_03