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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459130Generated: October 30, 2026

3,5-Difluorophenol → HCID 58823017, compound

https://huagongshe.com/reaction/459130

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-DifluorophenolHCID 75928—
Reactant(2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acidHCID 69424952—
ProductHCID 58823017HCID 58823017—

Reaction Steps

The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 3,5-difluorophenol and cleavage from the resin (Standard Procedure G) gave an oily solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-e16c78537f1e4df0b0882dbac1703d4a
Source noteuspto-grants-2007_03