HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cumylphenol → (2S)-2-Methoxy-3-(4-{3-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-propoxy}-phenyl)-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cumylphenol | HCID 11742 | — |
| Reactant | (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid | HCID 69424952 | — |
| Product | (2S)-2-Methoxy-3-(4-{3-[4-(1-methyl-1-phenyl-ethyl)-phenoxy]-propoxy}-phenyl)-propionic acid | HCID 58822850 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 4-cumylphenol and cleavage from the resin (Standard Procedure G) gave an oily solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-2198910ad8fc4d7180d20b00ccb458b2 |
| Source note | uspto-grants-2007_03 |