HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl 4-Hydroxybenzoate → 4-{3-[4-(2-Carboxy-2-methoxy-ethyl)-phenoxy]-propoxy}-benzoic acid benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl 4-Hydroxybenzoate | HCID 7180 | — |
| Reactant | (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid | HCID 69424952 | — |
| Product | 4-{3-[4-(2-Carboxy-2-methoxy-ethyl)-phenoxy]-propoxy}-benzoic acid benzyl ester | HCID 69422771 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with benzyl 4-hydroxybenzoate and cleavage from the resin (Standard Procedure G) gave an oily solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-feb7c690489a4d6cb19264406e51ac99 |
| Source note | uspto-grants-2007_03 |