6-Hydroxyflavone → (2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-chroman-6-yloxy)-propoxy]-phenyl}-propionic acid

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	6-Hydroxyflavone	HCID 72279	—
Edukt	(2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid	HCID 69424952	—
Produkt	(2S)-2-Methoxy-3-{4-[3-(4-oxo-2-phenyl-chroman-6-yloxy)-propoxy]-phenyl}-propionic acid	HCID 58822982	—

Reaktionsschritte

The title compound was prepared from (2S)-3-[4-(3-Hydroxy-propoxy)-phenyl]-2-methoxy-propionic acid linked to Wang's Resin (Example 94, Step D) via Mitsunobu coupling with 6-hydroxyflavone and cleavage from the resin (Standard Procedure G) gave an oily solid.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US07192982B2
Quelldatensatz	uspto-grants-2007_03
ORD ID	ord-7f99744399194c24839dd147dceb4621
Quellennotiz	uspto-grants-2007_03