HCID 10112472, compound → HCID 58822959, compound

Participants

Reaction Steps

The title compound was prepared as follows: (2S)-3-{4-[5-(Biphenyl-4-yloxy)-pent-1-ynyl]-phenyl}-2-methoxy-propionic acid from Example 21 (0.08 mmol) was dissolved in methanol (10 mL). Palladium 10% on activated carbon (0.004 g, 0.004 mmol) was added and the solution saturated with hydrogen (1 Atm) and stirred for 5 hours. The mixture was filtered through a pad of celite and concentrated under vacuum. The residue was purified by column chromatography. MS (ES) for C27H30O4 [M−H]−: 417.3.

Provenance & Evidence