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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459184Generated: October 30, 2026

[4-(3-Bromopropoxy)phenyl]phenylmethanone → 3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-methyl-phenyl}-2-methoxy-propionic acid

https://huagongshe.com/reaction/459184

Reaction equation

Participants

RoleNameHCIDCharge
Reactant[4-(3-Bromopropoxy)phenyl]phenylmethanoneHCID 19011983—
Reactant3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl esterHCID 58822833—
Product3-{4-[3-(4-Benzoyl-phenoxy)-propoxy]-3-methyl-phenyl}-2-methoxy-propionic acidHCID 18443622—

Reaction Steps

A mixture of 3-(4-Hydroxy-3-methyl-phenyl)-2-methoxy-propionic acid ethyl ester and from Example 162, Step E and [4-(3-Bromo-propoxy)-phenyl]-phenyl-methanone were treated under standard condition I to give the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-42236658d61e42238c672c051545ac35
Source noteuspto-grants-2007_03