Lithium Hydroxide → HCID 18443550, compound

Participants

Reaction Steps

The title compound was prepared from (2S)-3-{4-[4-(Biphenyl-4-yloxy)-butoxy]-phenyl}-2-methoxy-propionic acid ethyl ester from Step C under the standard Hydrolysis procedure C. (LiOH). 1H-NMR (200.15 MHz, CDCl3): 7.57–7.49 (m, 4H); 7.45–7.37 (m, 2H); 7.32–7.11 (m, 3H); 6.97 (d, 2H, J=8.9); 6.84 (d, 2H, J=8.9); 4.11–3.93 (m, 5H); 3.40 (s, 3H); 3.10 (dd, 1H, J=14.0, 4.3); 2.96 (dd, 1H, J=14.5, 7.0); 1.99–1.97 (m, 4H) ppm.

Provenance & Evidence