HCID 18443682, compound → 4-(Benzyloxy)-2-chlorobenzaldehyde

HRID 459209Notes

Reaction equation

HRID 459209 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][OH:16])=[C:11]([Cl:17])[CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>ClCCl.O=[Mn]=O>[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([CH:15]=[O:16])=[C:11]([Cl:17])[CH:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 1

HCID 18443682HCID 18443682, compound

Product 1

HCID 140340774-(Benzyloxy)-2-chlorobenzaldehyde

Reagents, catalysts & solvents 2

HCID 14801Manganese dioxideCatalystHCID 6344DichloromethaneSolvent

Procedure

To a solution of (4-Benzyloxy-2-chloro-phenyl)-methanol in dichloromethane, MnO2 (10 eq) were added and the mixture reaction stirred overnight. Filtered through a pad of celite and purified by chromatography in silica gel to give the title product.

Workup

  1. customthe mixture reaction
  2. filtrationFiltered through a pad of celite
  3. custompurified by chromatography in silica gel

Sources & evidence

ORD record
ord-4d2a72e663aa4d1c8863e6081abd266f
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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