HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Benzoyl-2-naphthol → (2S)-3-{4-[3-(6-Benzoyl-naphthalen-2-yloxy)-propoxy]-phenyl}-2-methoxy-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Benzoyl-2-naphthol | HCID 93271 | — |
| Reactant | (2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 58822859 | — |
| Product | (2S)-3-{4-[3-(6-Benzoyl-naphthalen-2-yloxy)-propoxy]-phenyl}-2-methoxy-propionic acid | HCID 18443519 | — |
Reaction Steps
(2S)-3-[4-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 173, Step A was treated with (6-Hydroxy-naphthalen-2-yl)-phenyl-methanone under the Standard Procedure J. The compound thus obtained was allowed to react under Standard hydrolysis procedure C(NaOH) to give the title compound. MS(ES) for C30H28O6 [M+Na]+: 507, [M+H]+: 485.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-888c2184cb2f4ac79c93e2418acf7586 |
| Source note | uspto-grants-2007_03 |