Sodium Hydroxide → HCID 58822849, compound

HRID 459224Notes

Reaction equation

HRID 459224 reaction equation
C([O:3][C:4](=[O:20])[C@@H:5]([O:18][CH3:19])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16]Br)=[CH:9][CH:8]=1)C.[O:21]1[C:25]2[CH:26]=[CH:27][C:28]([OH:30])=[CH:29][C:24]=2[O:23][CH2:22]1.[OH-].[Na+]>>[O:21]1[C:25]2[CH:26]=[CH:27][C:28]([O:30][CH2:16][CH2:15][CH2:14][O:13][C:10]3[CH:9]=[CH:8][C:7]([CH2:6][C@H:5]([O:18][CH3:19])[C:4]([OH:3])=[O:20])=[CH:12][CH:11]=3)=[CH:29][C:24]=2[O:23][CH2:22]1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 68289SesamolHCID 58822859(2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl ester

Product 1

HCID 58822849HCID 58822849, compound

Procedure

(2S)-3-[4-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 173, Step A was treated with Benzo[1,3]dioxol-5-ol under the Standard Procedure J. The compound thus obtained was allowed to react under Standard hydrolysis procedure C (NaOH) to give the title compound. MS(ES) for C20H22O7 [M+Na]+: 397, [M+H]+: 375.

Workup

  1. customThe compound thus obtained

Sources & evidence

ORD record
ord-60c09beb29e645bb9c6c630af1af80f7
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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