Sodium Hydroxide → HCID 58822571, compound

HRID 459232Notes

Reaction equation

HRID 459232 reaction equation
C([O:3][C:4](=[O:20])[C@@H:5]([O:18][CH3:19])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16]Br)=[CH:9][CH:8]=1)C.[CH:21]1[C:29]2[C:28]3[CH:30]=[CH:31][CH:32]=[CH:33][C:27]=3[O:26][C:25]=2[C:24]([C:34]2[CH:39]=[CH:38][C:37]([OH:40])=[CH:36][CH:35]=2)=[CH:23][CH:22]=1.[OH-].[Na+]>>[CH:21]1[C:29]2[C:28]3[CH:30]=[CH:31][CH:32]=[CH:33][C:27]=3[O:26][C:25]=2[C:24]([C:34]2[CH:39]=[CH:38][C:37]([O:40][CH2:16][CH2:15][CH2:14][O:13][C:10]3[CH:9]=[CH:8][C:7]([CH2:6][C@H:5]([O:18][CH3:19])[C:4]([OH:3])=[O:20])=[CH:12][CH:11]=3)=[CH:36][CH:35]=2)=[CH:23][CH:22]=1

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 18443691HCID 18443691, compoundHCID 58822859(2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl ester

Product 1

HCID 58822571HCID 58822571, compound

Procedure

(2S)-3-[4-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester from 0, Step A was treated with 4-Dibenzofuran-4-yl-phenol from Step A under the Standard Procedure J. The compound thus obtained was allowed to react under Standard hydrolysis procedure C (NaOH) to give the title compound. MS(ES) for C31H30O6 [M+Na]+: 519.

Workup

  1. customThe compound thus obtained

Sources & evidence

ORD record
ord-88e908bf8c384fdd9b7216b76d354518
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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