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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459237Generated: October 29, 2026

Sodium Hydroxide → HCID 58822558, compound

https://huagongshe.com/reaction/459237

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
Reactant3'-(Trifluoromethoxy)[1,1'-biphenyl]-4-olHCID 20816520—
Reactant(2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl esterHCID 58822859—
ProductHCID 58822558HCID 58822558—

Reaction Steps

(2S)-3-[4-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester from Example 173, Step A was treated with 3′-Trifluoromethoxy-biphenyl-4-ol from Step A under the Standard Procedure J. The compound thus obtained was allowed to react under Standard hydrolysis procedure C (NaOH) to give the title compound. MS(ES) for C26H25F3O6 [M+Na]+: 513, [M+H]+: 491.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-06aaa80a8e2a407d97723a839ec3c0e5
Source noteuspto-grants-2007_03