HCID 69424971, compound → HCID 69427876, compound

Participants

Reaction Steps

A solution of 4-Benzyloxyphenyl-2-(4-chlorophenoxy)propanoic acid methyl ester in ethanol with 10% Pd/C (5 wt %) was stirred under hydrogen atmosphere (1 tm) over 2 hours. The catalyst was removed via filtration through a pad of celite and the filtrated concentrated in vacuo to produce the title compound (90%). 1H-NMR (200.15 MHz, CDCl3): δ 7.25–7.14 (m, 4H), 7.94–7.73 (m, 4H), 4.81–4.69 (m, 1H), 3.70 (s, 3H), 3.16 (d, 2H, J=4.1).

Provenance & Evidence