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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459271Generated: October 26, 2026

4-(3-Bromopropoxy)1-phenoxybenzene → (S)-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-2-propoxy-propionic acid ethyl ester

https://huagongshe.com/reaction/459271

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(3-Bromopropoxy)1-phenoxybenzeneHCID 11255243—
Reactant(S)-3-(4-hydroxy-phenyl)-2-propoxy-propionic acid ethyl esterHCID 58822755—
Product(S)-3-{4-[3-(4-phenoxy-phenoxy)-propoxy]-phenyl}-2-propoxy-propionic acid ethyl esterHCID 58822857—

Reaction Steps

The title compound was prepared from (S)-3-(4-hydroxy-phenyl)-2-propoxy-propionic acid ethyl ester and 3-(4-phenoxy-phenoxy)-propyl bromide (Example 244) using the Standard Procedure L. The product was purified by column chromatography on silica gel using 9/1 Hexan/Ethyl acetate mixture as eluent to afford the title product. MS(ES) for C29H34O6 [M+NH4]+: 496.3

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-03dfefd6370e4996b6a8ec3294fea298
Source noteuspto-grants-2007_03