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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 459278Generated: October 25, 2026

Sodium Hydroxide → (2S)-4'-{3-[4-(2-Carboxy-2-methoxy-ethyl)-2-methoxy-phenoxy]-propoxy}-biphenyl-4-carboxylic acid

https://huagongshe.com/reaction/459278

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantMethan(2H)olHCID 123113—
Reactant(2S)-4'-{3-[2-Methoxy-4-(2-methoxy-2-methoxycarbonyl-ethyl)-phenoxy]-propoxy}-biphenyl-4-carboxylic acid methyl esterHCID 58822569—
Product(2S)-4'-{3-[4-(2-Carboxy-2-methoxy-ethyl)-2-methoxy-phenoxy]-propoxy}-biphenyl-4-carboxylic acidHCID 58822805—

Reaction Steps

The title compound was prepared from 4′-{3-[2-methoxy-4-(2-methoxy-2-methoxycarbonyl-ethyl)-phenoxy]-propoxy}-biphenyl-4-carboxylic acid methyl ester (Step B) by standard hydrolysis procedure C (NaOH). 1H-NMR (MeOD, 300.15 MHz):

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07192982B2
Source datasetuspto-grants-2007_03
ORD IDord-7f44fe3c8ae64e36bc7bbf46fdf91b87
Source noteuspto-grants-2007_03