Cyclohexane, (bromomethyl)- → HCID 58822554, compound

HRID 459286Notes

Reaction equation

HRID 459286 reaction equation
C([O:3][C:4](=[O:27])[C@@H:5]([O:25][CH3:26])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:23]=[CH:22][C:21]([OH:24])=[CH:20][CH:19]=2)=[CH:9][CH:8]=1)C.Br[CH2:29][CH:30]1[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]1>>[CH:30]1([CH2:29][O:24][C:21]2[CH:20]=[CH:19][C:18]([O:17][CH2:16][CH2:15][CH2:14][O:13][C:10]3[CH:9]=[CH:8][C:7]([CH2:6][C@H:5]([O:25][CH3:26])[C:4]([OH:3])=[O:27])=[CH:12][CH:11]=3)=[CH:23][CH:22]=2)[CH2:35][CH2:34][CH2:33][CH2:32][CH2:31]1

Participants

3

Reactant 2

HCID 137636Cyclohexane, (bromomethyl)-HCID 58822797HCID 58822797, compound

Product 1

HCID 58822554HCID 58822554, compound

Procedure

The title compound was prepared from (2S)-3-{4-[3-(4-hydroxy-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid ethyl ester (Example 263, Step B) and (bromomethyl)cyclohexane following the procedure described for Example 264.

Sources & evidence

ORD record
ord-ef69bb3f97484c77b3ff6071a41b1ffb
Source dataset
uspto-grants-2007_03
Patent number
US07192982B2

Reaction notes

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