Ethyl [(methanesulfonyl)oxy]acetate → HCID 69423428, compound

Participants

Reaction Steps

The title compound was prepared from (2S)-3-{4-[3-(4-hydroxy-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid ethyl ester (Example 263, Step B) and methane-sulfonyloxy-acetic acid ethyl ester (Step A) by following the procedure described for Example 264. 1H-NMR (MeOD, 200.15 MHz): δ 7.13 (d, 2H, J=8.6), 6.86–6.81 (m, 6H), 4.57 (s, 2H), 4.15–4.06 (m, 4H), 3.91 (dd, 1H, J=7.8, 4.8), 3.31 (s, 3H), 2.99 (dd, 1H, J=14.2, 4.6), 2.85 (dd, 1H, J=14.2, 7.5), 2.17 (qn, 2H, J=6.2).

Provenance & Evidence