HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Morpholinophenol → (2S)-2-methoxy-3-{4-[3-(3-morpholin-4-yl-phenoxy)-propoxy]-phenyl}-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Morpholinophenol | HCID 141343 | — |
| Reactant | (2S)-3-[4-(3-Bromopropoxy)-phenyl]-2-methoxy-propionic acid ethyl ester | HCID 58822859 | — |
| Reactant | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| Product | (2S)-2-methoxy-3-{4-[3-(3-morpholin-4-yl-phenoxy)-propoxy]-phenyl}-propionic acid | HCID 58822621 | — |
Reaction Steps
The title compound was prepared from (2S)-3-[4-(3-bromo-propoxy)-phenyl]-2-methoxy-propionic acid ethyl ester (Example 284, Step 2) and 3-Morpholin-4-yl-phenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1), to produce a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07192982B2 |
| Source dataset | uspto-grants-2007_03 |
| ORD ID | ord-22e7d333a1da424d8971427b93a934da |
| Source note | uspto-grants-2007_03 |