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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 459352Erstellt: 25. Oktober 2026

2-Isopropylphenol → 3-{3-[3-(2-Isopropyl-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acid

https://huagongshe.com/reaction/459352

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt2-IsopropylphenolHCID 6943—
Edukt3-[3-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl esterHCID 58822861—
Edukt(2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acidHCID 58822897—
Produkt3-{3-[3-(2-Isopropyl-phenoxy)-propoxy]-phenyl}-2-methoxy-propionic acidHCID 18443595—

Reaktionsschritte

The title compound was prepared from 3-[3-(3-bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester (Example 323, Step 1) and 2-isopropylphenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1). The enatiomers were separated by chiral HPLC. MS (ES) for C22H28O5 [M+Na]+: 395.4.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07192982B2
Quelldatensatzuspto-grants-2007_03
ORD IDord-846b6e6448b94faca4b20da3beefaf6a
Quellennotizuspto-grants-2007_03