化工社化工社 化学情報印刷レポート · 研究参考用
3-Methoxyphenol → 2-Methoxy-3-{3-[3-(3-methoxy-phenoxy)-propoxy]-phenyl}-propionic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 3-Methoxyphenol | HCID 9007 | — |
| 反応物 | 3-[3-(3-Bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester | HCID 58822861 | — |
| 反応物 | (2S)-2-methoxy-3-[4-(3-phenoxy propoxy)-phenyl]-propionic acid | HCID 58822897 | — |
| 生成物 | 2-Methoxy-3-{3-[3-(3-methoxy-phenoxy)-propoxy]-phenyl}-propionic acid | HCID 18443263 | — |
反応手順
The title compound was prepared from 3-[3-(3-bromo-propoxy)-phenyl]-2-methoxy-propionic acid methyl ester (Example 323, Step 1) and 3-methoxyphenol via the same procedure used for the preparation of (2S)-2-methoxy-3-[4-(3-phenoxy-propoxy)-phenyl]-propionic acid (Example 285, Step 1). The enatiomers were separated by chiral HPLC. MS (ES) for C20H24O6 [M+Na]+: 383.3.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07192982B2 |
| 出典データセット | uspto-grants-2007_03 |
| ORD ID | ord-dcab3ed6b7b649dea829eedbfab40fbd |
| 出典メモ | uspto-grants-2007_03 |